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Session: PIV/PTV methods and applications V
Session starts: Thursday 06 November, 14:20
Presentation starts: 15:00
Room: Lecture room A

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Michael Jehan Pangestu (Laboratory for Turbulence Research in Aerospace and Combustion (LTRAC), Monash University)
Bihai Sun (Laboratory for Turbulence Research in Aerospace and Combustion (LTRAC), Monash University,)
Alireza Heidarian (Laboratory for Turbulence Research in Aerospace and Combustion (LTRAC), Monash University)
Vishal Chaugule (Laboratory for Turbulence Research in Aerospace and Combustion (LTRAC), Monash University)
Patrick He (Respiratory Technology, Woolcock Institute of Medical Research)
Hui Xin Ong (Macquarie Medical School, Department of Biological Sciences, Faculty of Medicine, Health and Human Sciences/Respiratory Technology, Woolcock Institute of Medical Research)
Imco Sibum (Resyca B.V,)
Wietze Nijdam (Medspray B.V)
Nicolas Buchmann (Resyca B.V)
Daniela Traini (Respiratory Technology, Woolcock Institute of Medical Research/Macquarie Medical School, Department of Biological Sciences, Faculty of Medicine, Health and Human Sciences)
Julio Soria (Laboratory for Turbulence Research in Aerospace and Combustion (LTRAC), Monash University)

Abstract:
Innovations in inhaler technology have resulted in the development of low-velocity spray devices called soft mist inhalers (SMIs). The SMI is a propellant-free multidose inhaler device that does not suffer from the ‘ballistic effects’ of aerosols associated with other inhaler technologies. This study uses advanced laser-based imaging methodologies to measure the instantaneous 2-component – 2-dimensional (2C-2D) air velocity field using particle image velocimetry (PIV) and the associated 2C-2D water mist droplet velocity field using particle tracking velocimetry (PTV) for the Resyca® Pre-Filled Syringe Inhaler (PFSI) soft mist inhaler (SMI) under typical operating conditions. These high-fidelity measurements provide detailed information of the corresponding air and water mist droplet velocity distributions and their relationship for this SMI. PIV is a non intrusive optical measurement technique used to measure the instantaneous fluid velocity within a measurement volume. The local fluid motion is determined from the cross-correlation of single-exposed image pairs of tracer particles illuminated by two coincident laser sheets produced by a dual-cavity pulsed laser for the two corresponding exposures, where the laser pulses are temporally separated by a small time, ∆t. PTV measures the velocity of individual particles recorded in the image pair by detecting particles in each image and using the velocity measurements from PIV as a predictor to match the corresponding particle from the first to the second image [2]. The structure and relationship between the 2C-2D velocity measurement of the airflow and droplet kinematics aims to provide insights into the design of future inhaler devices. The spatial distribution of the first-order velocity statistics for the airflow and water mists droplets are presented and compared.